Pleasant tasting liquid laxative3/18/2024 ![]() ![]() I'm going to use patient ratings as a (very) rough indicator of what our choices are now and whether they are any better or worse than GoLYTELY, the gold standard of putridity – Four gallons of a vile salty-cherry tasting abomination that most of us (especially in the "almost time for a dirt nap crowd,") have either experienced or heard someon e else complain bitterly about. (See " 4 Prescription Drugs People Hate" if you don't believe me.) Nonetheless, if you look up a drug and its rating is below 2.5 or 3.0 out of 5, and there are some real doozies in the comments section, it's a pretty good bet that it's going to be all kinds of nasty. Gastroenterol 2019 Feb 01 114(2)305-314,ĭo these findings match what patients have to report on – the website I go to before I try a new medicine? The patient ratings and rants are descriptive and subjective, not scientific. GoLYTELY significantly underperformed in terms of prep tolerability compared with magnesium citrate, MiraLAX with Gatorade, MoviPrep, OsmoPrep, Prepopik/Clenpiq, and SUPREP. They range from "not that hideous" to "violation of the Geneva Convention hideous." The "good" news is that you do have some choices, which is made clear in a 2019 prospective study published in the Journal of Gastroenterology, which looked at the most commonly used bowel preparations (emphasis mine): ![]() You will return it, forcefully, but this transaction should not take place at the pharmacy. The real problem is a second gift that necessarily precedes the first - the dreaded colonoscopy prep, and it doesn't even come with a card. If you don't like it (you won't), don't worry. Although the image of a bassoon being force-fed into your anus isn't especially comforting, a colonoscopy is nothing more than a really good nap, thanks to the wonder drug propofol, something I wrote about in 2020. One icky but hugely important thing will be a birthday gift called a colonoscopy, which people fear mightily. But if you reach 50, welcome to the beginning of old age, where icky things start to happen to you. ![]() If you're lucky enough to have died at age 49, there is no need to read this. ![]()
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